miR-137 is a tumor suppressor in endometrial cancer and is repressed by DNA hypermethylation
نویسندگان
چکیده
منابع مشابه
miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer.
The etiology and development of human cancers that remain little understood might be enlightened by defining tumor suppressor microRNAs (TS-miRNA). In this study, we identified TS-miRNAs silenced by aberrant DNA hypermethylation in endometrial cancer. Functional screening of 327 synthetic miRNAs in an endometrial cancer cell proliferation assay identified 103 miRNAs that inhibited cell growth. ...
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ژورنال
عنوان ژورنال: Laboratory Investigation
سال: 2018
ISSN: 0023-6837,1530-0307
DOI: 10.1038/s41374-018-0092-x